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CRESTER®


CRESTER®

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SMALL DOSE, BIG MASS - EXTRA POTENT CREATINE!

Take creatine so your muscles can explode with more strength and another dimension. This is an excellent choice! ... Creatine transports energy from the place of its generation directly to the places where the power impulse is generated and the protein anabolism is stimulated.

However, monohydrate - the form of creatine most common in the body - consumed together with the supplement has this disadvantage - that to high degree it is converted into the inactive metabolite - creatinine. The conversion of creatine into creatinine is a reaction taking place without the participation of the enzymes and thus its speed is determined mainly by the environmental conditions in which the creatine particles are present at the time.  
It increases when the concentration of protons in the environment increases, i.e. when its pH is decreasing. The high concentration of protons is found in the gastric juice, therefore a substantial part of consumed creatine transformed here into creatinine is irrevocably lost. Only this part of creatine reaches the muscles, which survives the gastric juice environment.  

The survived part is stored though by the muscle cells but this does not mean that it is utilised completely and appropriately by these cells...

The concentration of protons increases rapidly during muscle work and maintains a high level  for some time after the end of its work, when the lactic acid created in excess as a result of intensive glucose burning,  becomes the main supplier of protons. In this situation a substantial part of the already stored creatine is again transformed into inactive creatinine leaves the body and is lost.

The supplementation with creatine monohydrate is accompanied by a paradox … This supplement is taken most often after training, as during this period creatine is absorbed most intensively into the muscle cells and stored in them most effectively through the cellular transport mechanism independent from the insulin, i.e. through the substrates phosphorylation.  This paradox concerns the fact that at the same time the conversion of creatine into inactive creatinine is very high!
In the end it results in the situation when instead of enjoying the anabolic and ergogenic activity of creatine monohydrate we have to take its supplements in irrationally high dosages. The higher the dosage of creatine monohydrate, the higher the burden on the body caused by inactive creatinine.

The studies conducted over the last decade have demonstrated, however, that creatinine, suspected of having a harmful effect on the health, does not actually have a negative impact on the body, but medical science follows the principle that the supplementation of any substance should strive to reduce the concentration of inactive metabolites, because the lower the concentration of metabolites, the lower the burden of the body caused by the processes associated with their elimination.
This results from another essential principle - the use of the minimum effective dose of every preparation. For example if the same desired metabolic effect can be obtained by taking 2 g of substance X and 1 g of substance Y, then usually the use of substance Y is encouraged because the lower the effective dose of a substance, the lower the burden on the body with the processes associated with its metabolism.
Seeking a more effective alternative for creatine monohydrate, scientists rediscovered the special properties of esters of carboxylic acids. Creatine ethyl ester (CrESTER) belongs to this group of chemical compounds.  
The low pH of the environment favours both the creation and disintegration of ester bonds.  

When the concentration of protons is high, but the ambient temperature moderate, the creatine ethyl ester shows a stronger trend towards stabilisation of its structure. This enables it to pass without harm through the stomach content and be easily absorbed in a nearly unchanged form by the muscle cells.  The ethyl esters of carboxylic acids are very well absorbed, because ester bonds change the properties of the carboxylic (acidic) group. This group usually prevents the penetration of biological barriers and the substances equipped with it have to use special protein transporters to penetrate the tissues.  

When the concentration of protons and temperature increase at the same time, which occurs in the muscle cells during work, ester disintegrates releasing active creatine to generate the power impulse. However, despite this action it still remains in loose association with it determined by the balance constant. Therefore, when creatine could be converted into inactive creatinine, it is again subject to esterification - it is not lost - but stored instead.  

During the resting period, when pH and the cellular environment temperature are within the physiologically optimum ranges, creatine is released from its ester bonds by enzymes from the esterase group and directed to the tasks related to the anabolism of muscle proteins. As ethyl esters are relatively resistant to the impact of esterase, creatine is released here continuously and regularly, which enables the uninterrupted supply of creatine to anabolic processes and at the same time minimises the trend of conversion into inactive creatinine.  

CrESTER has a clear advantage over traditional creatine monohydrate. Its effective dose is a lot smaller than the effective dose of monohydrate. It can be used in substantially smaller quantities, with a lot higher anabolic and ergogenic effect and in this way strengthen and develop the muscle mass without burdening the body with the ballast of the redundant inactive creatinine.
CrESTER is an exceptional form of creatine of very high stability and excellent solubility.

CrESTER is dedicated to physically active individuals and professional sportsmen as a preparation supporting exercising adaptation - specifically the development of muscle strength and mass.  
Each capsule of BIOGENIX CrESTER contains 800 mg of highest quality creatine ethyl ester - CEE HCL (Creatine Ethyl Ester HCL)

creatine ethyl ester HCl, bulking agent – microcrystalline cellulose, anti-caking agent – magnesium stearate, capsule cover – gelatine.

Nutrition value
2 capsules
Creatine ethyl ester HCI 2200 mg


3-4 capsules taken 1-2 times a day with plenty of water.
In order to obtain the optimum results the preparation can be taken together with Bx AERO2, Bx GLUCETYL, Bx NITRO Bx, Bx M3 Creatine or as a supplement in the quantity of 2-3 capsules for each portion of Bx CELL PUMP.
CRESTER®

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